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Shared Genetic Variant Found Between Gum Disease and Coronary Heart Disease

From Shawn Watson, About.com GuideMay 26, 2009

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Scientists at the universities of Kiel, Dresden, Amsterdam and Bonn have identified a genetic link between coronary heart disease and periodontitis (gum disease). The discovery was presented at the European Society of Human Genetics on May 25, 2009.

In a press release from the University of Keil, Germany, Dr. Arne Schaefer was quoted in saying his team has "examined the aggressive form of periodontitis, the most extreme form of periodontitis which is characterized by a very early age of onset. The genetic variation associated with this clinical picture is identical to that of patients who suffer from cardiovascular disease and have already had a myocardial infarction." The genetic variant was found on chromosome 9.

Dr. Schaefer also stresses that "Aggressive periodontitis has shown itself to be associated not only with the same risk factors such as smoking, but it shares, at least in parts, the same genetic predisposition with an illness that is the leading cause of death worldwide."

The connection between coronary heart disease (CDH) and periodontal disease should be taken very seriously. Coronary heart disease is the leading cause of death for men and women in the United States. Because it has to be assumed that there is a causal connection between periodontitis and myocardial infarction, patients with a history of CDH could see aggressive periodontal treatments become a regular part of their treatment regime, and the same could be said about periodontal disease. Dentists that diagnose periodontal disease could be sending referrals to cardiologists in the future; connecting diagnosed gum disease to other risk factors for coronary heart disease displayed in some patients.

Comments
June 1, 2010 at 7:05 am
(1) Zdrowie says:

I just sent this post to a bunch of my friends as I agree with most of what you’re saying here and the way you’ve presented it is awesome.

June 2, 2010 at 1:26 pm
(2) Wakacje says:

I’ve been visiting your blog for a while now and I always find a gem in your new posts. Thanks for sharing.

June 27, 2010 at 5:34 pm
(3) Toronto Dentist in Etobicoke says:

Great information Shawn.

People take gum disease far too lightly. It’s like having an open portal to the bloodstream for bacteria to enter.

Gum disease puts a heavy burden on the immune system and the inflammatory response tends to harm other parts of the body.

Statistically speaking, Hygienists save lives. By keeping any gum disease under control, people are much less susceptible to fatal heart attacks.

Joe Bulger DDS
Visit my dental blog – Toronto Dentist Smile Blog

August 27, 2010 at 5:54 pm
(4) Toronto Dentists Etobicoke says:

Some hospitals advocate oral hygiene workup prior to surgery, particularly heart surgery. No question bugs in the mouth do harm as they enter the blood stream.

Joe :D

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